US Inventories

US TSCA Inventory

Section 8 (b) of the Toxic Substances Control Act (TSCA) requires EPA to compile, keep current, and publish a list of each chemical substance that is manufactured or processed in the United States. Since EPA published the final TSCA Inventory Reporting Rule on December 23, 1977, the TSCA Inventory has grown to include the identities of over 83,000 chemical substances.

If an intended manufacturer or importer of a chemical substance is unsure of the TSCA Inventory status of the chemical (e.g., cannot find that substance on one of the public sources of non-confidential TSCA Inventory data), the company or representative can obtain a written determination from EPA if it can demonstrate a “genuine intent.” It can do this by submitting a Bona Fide Intent to Manufacture or Import Notice pursuant to the procedures at 40 CFR section 720.25.

Substances not on the TSCA Inventory are considered “new” chemicals and shall be notified to EPA through Premanufacture Notice (PMN). However, there are exemptions for PMN.

Testing Marketing: Manufacturers are permitted to assess the commercial viability of a new chemical and to receive customer feedback before filing a PMN. Use of this exemption requires submission of an application for Test Marketing Exemption to EPA.

Low Volume: Manufacturers can produce low volumes (up to 10,000 kg) of certain new chemical substances without full PMN review under the Low Volume Exemption (LVE). Use of this exemption requires submission of Form 7710-25 (the standard PMN form) to EPA.

Low Release / Low Exposure: EPA provides the LoREX exemption for chemical substances with low environmental releases and human exposure. Prior approval is required.
R&D, polymer and export only: Prior approval is not required.

OSHA Occupational Chemical Database

OSHA maintains this chemical database as a convenient reference for the occupational safety and health community. It compiles information from several government agencies and organizations.

Information available in the report includes:

  • Physical Properties
  • Exposure Guidelines
  • NIOSH Pocket Guide, and
  • Emergency Response Information, including the DOT Emergency Response Guide.

This database originally was developed by OSHA in cooperation with EPA.

List of Chemicals: